Our People
The Eck laboratory is made up of a collaborative mix of graduate students, research fellows, and scientific staff. Lab members come from multiple backgrounds including biochemistry, biophysics, chemistry, and molecular biology.
Michael Eck
Principal Investigator
Longwood Center, LC 4313
Michael_Eck (at) dfci.harvard.edu
eck (at) crystal.harvard.edu
Dr. Eck received his M.D. and Ph.D. in Biochemistry from the University of Texas Southwestern Medical School. He completed his Postdoctoral training under Dr. Stephen Harrison in Structural Biology at the Boston Children's Hospital and the Harvard Medical School before joining DFCI in 1996. Dr. Eck is currently a Professor of Biological Chemistry and Molecular Pharmacology at the Dana-Farber Cancer Institute and Harvard Medical School. His research focuses on the structure and regulation of tyrosine kinases in cancer and on structure-based approaches to discovery of novel inhibitors. The Eck lab also studies the structure of formin proteins and their role in assembling the actin cytoskeleton.
Principal Investigator
Longwood Center, LC 4313
Michael_Eck (at) dfci.harvard.edu
eck (at) crystal.harvard.edu
Dr. Eck received his M.D. and Ph.D. in Biochemistry from the University of Texas Southwestern Medical School. He completed his Postdoctoral training under Dr. Stephen Harrison in Structural Biology at the Boston Children's Hospital and the Harvard Medical School before joining DFCI in 1996. Dr. Eck is currently a Professor of Biological Chemistry and Molecular Pharmacology at the Dana-Farber Cancer Institute and Harvard Medical School. His research focuses on the structure and regulation of tyrosine kinases in cancer and on structure-based approaches to discovery of novel inhibitors. The Eck lab also studies the structure of formin proteins and their role in assembling the actin cytoskeleton.
Hyesung Jeon
Lead Scientist
Longwood Center, LC 4311
hjeon (at) crystal.harvard.edu
Dr. Jeon earned her PhD in Chemistry and Biophysics from the Graduate School of Arts and Sciences at Boston University. Dr. Jeon is an experienced, independent structural biologist specializing in molecular electron microscopy with a long-term interest in cell surface receptors and their interactions with ligands and intracellular signaling components. She works with multiple structural biology groups at DFCI including the Blacklow and Eck lab. In addition to her talents as an electron microscopist, Dr. Jeon has experience in X-Ray Crystallography, and broad skills as a cell biologist and protein biochemist. She has authored or co-authored more than forty publications over the past decade, and trained a number of successful graduate students and postdoctoral fellows.
Eunyoung Park
Senior Scientist
Longwood Center, LC 4302
eunyoung (at) crystal.harvard.edu
Dr. Park received her Ph.D. in Biochemistry in the lab of Dr. Hyun Kyu Song at Korea University. She completed her Postdoctoral training in Dr. Songs lab, which centered around Protein Crystallography and Biochemical Studies. She joined the Eck lab in 2010 and is focused on understanding the substrate recognition mechanism of proteosomal degradation that might better inform the understanding of many diseases including cancer and neurodegenerative disease. She is also an important communicator in the lab and has mentored her junior colleagues during her time in the lab. Dr. Park also dedicates her time to volunteer work in teaching at various science camps, educating young children.
Senior Scientist
Longwood Center, LC 4302
eunyoung (at) crystal.harvard.edu
Dr. Park received her Ph.D. in Biochemistry in the lab of Dr. Hyun Kyu Song at Korea University. She completed her Postdoctoral training in Dr. Songs lab, which centered around Protein Crystallography and Biochemical Studies. She joined the Eck lab in 2010 and is focused on understanding the substrate recognition mechanism of proteosomal degradation that might better inform the understanding of many diseases including cancer and neurodegenerative disease. She is also an important communicator in the lab and has mentored her junior colleagues during her time in the lab. Dr. Park also dedicates her time to volunteer work in teaching at various science camps, educating young children.
Byunghak Ha
Senior Scientist
Longwood Center, LC 4302
bhak (at) crystal.harvard.edu
Dr. Ha received his Ph.D. in Biological Science from the Seoul National University. He completed his postdoctoral training in Dr. Titus Boggon's lab at Yale University. He joined the Eck lab in 2020 and is involved in BRAF kinase research.
Senior Scientist
Longwood Center, LC 4302
bhak (at) crystal.harvard.edu
Dr. Ha received his Ph.D. in Biological Science from the Seoul National University. He completed his postdoctoral training in Dr. Titus Boggon's lab at Yale University. He joined the Eck lab in 2020 and is involved in BRAF kinase research.
Anna Schmoker
Scientist I
Longwood Center, LC 4302
Dr. Schmoker received her Ph.D. in Biology from the University of Vermont in 2020, where she studied cell signaling in development and cancer using biochemistry and protein mass spectrometry in the lab of Dr. Bryan Ballif. She joined the Eck lab in 2020.
Scientist I
Longwood Center, LC 4302
Dr. Schmoker received her Ph.D. in Biology from the University of Vermont in 2020, where she studied cell signaling in development and cancer using biochemistry and protein mass spectrometry in the lab of Dr. Bryan Ballif. She joined the Eck lab in 2020.
Emilie Leroy
Postdoctoral Research Fellow
Longwood Center, LC 4302
eleroy (at) crystal.harvard.edu
Dr. Leroy received a Ph.D in Biomedical and Pharmaceutical Sciences from the Université Catholique de Louvain (Brussels, Belgium) while in the lab of Pr. SN Constantinescu, where she studied the structure and function of JAK2 mutants involved in blood disorders. Although her current research focuses on structural biology, she initially specialized in biochemistry, cell biology and signaling.
Postdoctoral Research Fellow
Longwood Center, LC 4302
eleroy (at) crystal.harvard.edu
Dr. Leroy received a Ph.D in Biomedical and Pharmaceutical Sciences from the Université Catholique de Louvain (Brussels, Belgium) while in the lab of Pr. SN Constantinescu, where she studied the structure and function of JAK2 mutants involved in blood disorders. Although her current research focuses on structural biology, she initially specialized in biochemistry, cell biology and signaling.
Tyler Beyett
Postdoctoral Research Fellow
Longwood Center, LC 4302
tbeyett (at) crystal.harvard.edu
Dr. Beyett received his Ph.D. in Chemical Biology from the University of Michigan in the lab of Dr. John J.G. Tesmer, where he studied the structure and pharmacology of GPCR and NF-kB kinases. He joined the Eck lab in 2018 and focuses on combination drug therapies targeting EGFR in lung cancer, for which he received a Ruth L. Kirschstein National Research Service Award.
Postdoctoral Research Fellow
Longwood Center, LC 4302
tbeyett (at) crystal.harvard.edu
Dr. Beyett received his Ph.D. in Chemical Biology from the University of Michigan in the lab of Dr. John J.G. Tesmer, where he studied the structure and pharmacology of GPCR and NF-kB kinases. He joined the Eck lab in 2018 and focuses on combination drug therapies targeting EGFR in lung cancer, for which he received a Ruth L. Kirschstein National Research Service Award.
Javier Vinals Camallonga
Postdoctoral Research Fellow
Longwood Center, LC 4302
jcamallonga (at) crystal.harvard.edu
Dr. Vinals Camallonga received his Ph.D. in Biochemistry from the University of Oxford in the Lab of Dr. Anthony Watts, where he studied the structure and biophysical properties of archaerhodopsin-3 (AR3) in native and artificial membranes. He joined the Eck lab in 2020 to study tyrosine kinases.
Postdoctoral Research Fellow
Longwood Center, LC 4302
jcamallonga (at) crystal.harvard.edu
Dr. Vinals Camallonga received his Ph.D. in Biochemistry from the University of Oxford in the Lab of Dr. Anthony Watts, where he studied the structure and biophysical properties of archaerhodopsin-3 (AR3) in native and artificial membranes. He joined the Eck lab in 2020 to study tyrosine kinases.
Marina Candido Primi
Postdoctoral Research Fellow
Longwood Center, LC 4302
Dr. Primi received her M.Sc. and Ph.D. in Medicinal Chemistry from the University of Sao Paulo, Brazil. She was previously a postdoc at The Scripps Research Institute in the lab of Dr. Tina Izard studying the structure of cytoskeletal tumor suppressor proteins and developing inhibitors for Mycobacterium tuberculosis. Marina joined the Eck lab in 2021 and works on JAK inhibitors.
Postdoctoral Research Fellow
Longwood Center, LC 4302
Dr. Primi received her M.Sc. and Ph.D. in Medicinal Chemistry from the University of Sao Paulo, Brazil. She was previously a postdoc at The Scripps Research Institute in the lab of Dr. Tina Izard studying the structure of cytoskeletal tumor suppressor proteins and developing inhibitors for Mycobacterium tuberculosis. Marina joined the Eck lab in 2021 and works on JAK inhibitors.
Emre Tkacik
Graduate Student
Longwood Center, LC 4302
etkacik (at) crystal.harvard.edu
Emre joined the Eck lab in 2020 and is a graduate student in the Systems, Synthetic, and Quantitative Biology Program at HMS. He is working on RAF kinase signaling. Prior to Harvard, Emre attended the University of Maryland, Baltimore County and worked in the lab of Dr. Michael Summers.
Graduate Student
Longwood Center, LC 4302
etkacik (at) crystal.harvard.edu
Emre joined the Eck lab in 2020 and is a graduate student in the Systems, Synthetic, and Quantitative Biology Program at HMS. He is working on RAF kinase signaling. Prior to Harvard, Emre attended the University of Maryland, Baltimore County and worked in the lab of Dr. Michael Summers.
Hanchen Zhao
Graduate Student
Longwood Center, LC 4302
hanchen (at) crystal.harvard.edu
Hanchen obtained his B.S./M.S. dual degree in Biochemistry and Chemistry from Brandeis University. At Brandeis University, Hanchen gained experience as an undergraduate researcher in the Foxman laboratory, where he practiced crystal growth of small molecules and studied the theory of X-ray crystallography. Hanchen joined the Eck lab in 2017 and is studying EGFR exon 20 insertion variants.
Graduate Student
Longwood Center, LC 4302
hanchen (at) crystal.harvard.edu
Hanchen obtained his B.S./M.S. dual degree in Biochemistry and Chemistry from Brandeis University. At Brandeis University, Hanchen gained experience as an undergraduate researcher in the Foxman laboratory, where he practiced crystal growth of small molecules and studied the theory of X-ray crystallography. Hanchen joined the Eck lab in 2017 and is studying EGFR exon 20 insertion variants.
William Gazlay
Graduate Student
Longwood Center, LC 4302
gazlay (at) crystal.harvard.edu
Will joined the Eck Lab as part of a collaborative effort to complete his PhD in Chemistry at the University of Massachusetts-Boston working in the lab of Dr. Jason Evans. At UMass, he studied the positional sensitivity of synthetic triglycerides via mass spectrometry and performed bottom-up proteomics experiments. In the Eck Lab, he is working on phosphoproteomics.
Graduate Student
Longwood Center, LC 4302
gazlay (at) crystal.harvard.edu
Will joined the Eck Lab as part of a collaborative effort to complete his PhD in Chemistry at the University of Massachusetts-Boston working in the lab of Dr. Jason Evans. At UMass, he studied the positional sensitivity of synthetic triglycerides via mass spectrometry and performed bottom-up proteomics experiments. In the Eck Lab, he is working on phosphoproteomics.
Ilse Schaeffner
Research Technician
Longwood Center, LC 4302
ischaeffner (at) crystal.harvard.edu
Ilse earned her B.S. in Biochemistry and Molecular Biology from Wake Forest University in 2021. In addition to studying X-ray crystallography at Wake Forest, she also studied coronavirus spike protein structure using computational biology and molecular dynamics.
Research Technician
Longwood Center, LC 4302
ischaeffner (at) crystal.harvard.edu
Ilse earned her B.S. in Biochemistry and Molecular Biology from Wake Forest University in 2021. In addition to studying X-ray crystallography at Wake Forest, she also studied coronavirus spike protein structure using computational biology and molecular dynamics.
Krista Bradley
Research Technician
Longwood Center, LC 4302
kbradley (at) crystal.harvard.edu
Krista earned her B.S. in Biological Sciences from Wake Forest University in 2021. At Wake Forest, she worked with Dr. Cormac O'Donovan studying biomarkers related to burnout in physicians. In the Eck lab, Krista works on the structure and function of JAK kinase.
Research Technician
Longwood Center, LC 4302
kbradley (at) crystal.harvard.edu
Krista earned her B.S. in Biological Sciences from Wake Forest University in 2021. At Wake Forest, she worked with Dr. Cormac O'Donovan studying biomarkers related to burnout in physicians. In the Eck lab, Krista works on the structure and function of JAK kinase.
Sehee Oh
Research Technician
Longwood Center, LC 4302
sehee (at) crystal.harvard.edu
Research Technician
Longwood Center, LC 4302
sehee (at) crystal.harvard.edu
John Genova
Technical Director
Longwood Center, LC 3302
John_Genova (at) dfci.harvard.edu
Dr. Genova earned his Ph.D. in Physical Chemistry from Brown University. Dr. Genova joined the Eck lab as the Technical Director in 2015. John's primary goals are to maintain the necessary equipment for X-ray crystallographic data collection and to train personnel in the safe use of the equipment.
Technical Director
Longwood Center, LC 3302
John_Genova (at) dfci.harvard.edu
Dr. Genova earned his Ph.D. in Physical Chemistry from Brown University. Dr. Genova joined the Eck lab as the Technical Director in 2015. John's primary goals are to maintain the necessary equipment for X-ray crystallographic data collection and to train personnel in the safe use of the equipment.